Now Rosie O’Donnell is in a feud with David Letterman

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David Letterman is the latest fellow celebrity to land on Rosie O'Donnell's shit list, after he joked, referring to O'Donnell's engagement to girlfriend Michelle Rounds, during the monologue of Tuesday's Late Show:

"The woman she is marrying, her fiancee, was driving…and her car broke down. And guess what happened? Rosie pulls up right behind her in her tow truck."

O'Donnell understandably wasn't thrilled with the allusion to the stereotype of lesbians being mechanical, and responded with a mini-fusillade on The Rosie Show, set to air on OWN tonight. The feisty Queens native, who has had well-known beef in the past with Donald Trump and Elisabeth Hasselbeck among others, asked:

"Why is that Dave? Why? I don't remember making fun of you when you had sex with all your interns! I didn't do that. I didn't make fun of your rampant, throbbing heterosexuality, did I Dave?

Rosie also took a page from Letterman's book and named her Top Five Reasons Why I Will Not Do Your Program, which included: "When you had that heart surgery, you shouldn't have told the doctors to take out the whole thing," and "Not only do you appear to be antigay, you're anti-tow-truck driver and that just pisses me off."

O'Donnell's boss Oprah had her own issues with Letterman which actually antedated his infamous "Uma-Oprah" Oscars monologue, when he had pranked her once by making her pay for lunch when they were both at the same restaurant on vacation. And the Late Night host had famously pissed off a protective Sarah Palin in 2009 after making a crack about her daughters.

But that's Letterman's style of course, skirting the bounds of propriety at times, and later managing the fallout from his cutting tongue, smoothing over hurt feelings with the contrite, good guy, midwestern-sensibility Letterman persona. His snark should not be confused with Santorum-level homophobia. Time will tell if Letterman puts the fire out immediately, or fans the flames further.